More Info on Zyrtec-D Indications

How Does Zyrtec-D Work?

As mentioned, Zyrtec-D contains pseudoephedrine (Sudafed®) and cetirizine (Zyrtec®). Allergies occur when the body's immune system reacts to normally harmless substances that do not bother most people. This reaction is partly caused by the release of histamine from certain cells in the body. Cetirizine is an antihistamine, which means it blocks histamine from binding to histamine receptors and causing allergy symptoms. Since histamine is responsible for many of the symptoms of allergies, blocking it can be helpful. However, antihistamines are not helpful for nasal congestion, which is why cetirizine is combined with pseudoephedrine.
Pseudoephedrine is a nasal decongestant, and it works by constricting the blood vessels in the nose, helping to relieve nasal congestion. It is useful for relieving nasal congestion due to many causes, including allergies and the common cold.

Zyrtec-D Uses in Children

Zyrtec-D is approved for children age 12 and older. Talk with your child's healthcare provider before giving the medication to a younger child.

Off-Label Zyrtec-D Uses

On occasion, your healthcare provider may recommend Zyrtec-D for something other than allergies. Currently, there are no universally accepted off-label Zyrtec-D uses.
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Zyrtec-D Medicine

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