Stinging Nettle

Stinging nettle is often used as an herbal supplement for the treatment of allergies. The leaves of this plant also contain beta-sitosterol, a flavonoid that may also help lower cholesterol and treat an enlarged prostate. However, much more research is needed to confirm the effectiveness of this supplement for these various uses. Potential side effects of the product include diarrhea, sweating, and upset stomach.

What Is Stinging Nettle?

Stinging nettle is a plant that is well known for causing intensely painful stings that are caused by tiny hairs on the stems and leaves. This plant is used medicinally for a variety of different purposes (such as for allergy treatment) in herbal medicine.
 
(Click Stinging Nettle Benefits for more information about possible stinging nettle uses.)
 

How Does It Work?

The various parts of the stinging nettle plant (such as the roots or leaves) contain several different compounds that may have medicinal properties. For instance, the leaves contain quercetin, a flavonoid that may help with allergies by inhibiting histamine release from certain cells in the body. The leaves also contain several other flavonoids, such as beta-sitosterol (which may help lower cholesterol and treat an enlarged prostate).
 
The plant also contains compounds that may have pain-relieving, anti-inflammatory analgesic, numbing, antiviral, and antibacterial effects. Because it contains many different active components, it is likely that benefits of the herb are due to a combination of several of the different components.
 

Is Stinging Nettle Effective?

In general, there is not enough scientific evidence to suggest conclusively that the plant really is effective for most uses.
 However, early research shows promise for a few different uses (see Does Stinging Nettle Work? for more information).
 

Dosing Information

As with most dietary supplements, there is no well-established standard dosage for stinging nettle, although general guidelines may be obtained from a few clinical trials.
 
(Click Stinging Nettle Dosage for more information.)
 

Side Effects of Stinging Nettle

Even though it is a "natural" product, stinging nettle can cause side effects. Some of the reported side effects include:
 
  • Stomach upset
  • Sweating
  • Allergic reactions
  • Diarrhea.
     
(Click Stinging Nettle Side Effects to learn more, including potentially serious side effects that you should report immediately to your healthcare provider.)
 

Drug Interactions

Theoretically, stinging nettle may interact with a few medications (see Stinging Nettle Drug Interactions).
 

Safety of Stinging Nettle

Stinging nettle seems to be relatively safe for many people, especially when used in moderation. However, some people may be more likely to experience problems. Therefore, you should talk with your healthcare provider prior to taking stinging nettle medicinally if you have:
 
  • Diabetes
  • Kidney disease, such as kidney failure (renal failure)
  • Any chronic or severe medical condition
  • Any allergies, including allergies to foods, dyes, or preservatives.
     
Also, let your healthcare provider know if you are:
 
Make sure to tell your healthcare provider about all other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
 
(Click Is Stinging Nettle Safe? for more information, including any available warnings and precautions.)
 

What If I Take an Overdose?

It is not known exactly what to expect from an overdose of this supplement. If you think you or someone else may have taken too much, it is important to seek immediate medical attention.
 
(Click Stinging Nettle Overdose for more information.)
 

Storage Methods for Stinging Nettle

Refer to the label of your individual product for information on how to best store stinging nettle. Keep all medications and supplements out of the reach of children.
 
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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