Rhinocort Aqua Drug Interactions

If protease inhibitors or certain antifungals or antibiotics are taken with Rhinocort Aqua, drug interactions may occur that could lead to potentially serious side effects. Since these medicines can increase the level of Rhinocort Aqua in your blood, your healthcare provider may need to decrease your dosage. To help prevent Rhinocort Aqua drug interactions, tell your healthcare provider about all medicines you are taking.

 

Rhinocort Aqua Drug Interactions: An Overview

Rhinocort Aqua® (budesonide nasal spray) can potentially interact with other medications. Some of the medicines that may lead to Rhinocort Aqua drug interactions include:
 
  • Certain antibiotics or antifungals, such as:
o Clarithromycin (Biaxin®)
o Erythromycin (Ery-Tab®)
o Isoniazid (Nydrazid®)
o Itraconazole (Sporanox®)
o Ketoconazole (Nizoral®)
o Telithromycin (Ketek®)
  • Protease inhibitors, such as:

Rhinocort Aqua Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Rhinocort Aqua is combined with any of the drugs listed above.
 
Certain Antibiotics and Antifungals
Some antibiotics and antifungals can increase the level of Rhinocort Aqua in your blood, perhaps increasing your risk for side effects of Rhinocort Aqua. In particular, too much Rhinocort Aqua in your blood can suppress your body's ability to produce natural steroids, which can cause serious consequences. This interaction is most likely to be a problem for people who take both antibiotics and antifungals on a long-term basis. Your healthcare provider may need to decrease your Rhinocort Aqua dosage to prevent this interaction from occurring.
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;