Phenylephrine Side Effects

Some of the possible side effects of phenylephrine include dizziness, insomnia, and headaches. In most cases, side effects tend to be minor and are generally easy to treat. However, make sure to notify your healthcare provider right away if you develop serious side effects of this medication, such as chest pain, a slow heart rate, or difficulty breathing.

An Introduction to Phenylephrine Side Effects

As with any medicine, phenylephrine can cause side effects. However, not everyone who takes the medication will have problems. In fact, some people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are easily treated by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with phenylephrine. Your healthcare provider can discuss a more complete list of phenylephrine side effects with you.)

Side Effects of Phenylephrine to Report

Some side effects with phenylephrine are potentially serious and should be reported immediately to your healthcare provider. These include, but are not limited to:
  • High blood pressure (hypertension)
  • Chest pain
  • A slow heart rate (bradycardia)
  • Anxiety
  • Unusual sensations, such as tingling or pricking, in the hands or feet
  • Decreased urine production
  • Signs of an allergic reaction, such as:


    • An unexplained rash
    • Itching
    • Hives
    • Swelling of the mouth or throat
    • Wheezing
    • Difficulty breathing.


Bothersome Side Effects

Some of the possible bothersome (but not usually dangerous) side effects of phenylephrine include:
  • Dizziness
  • Pale skin
  • Excitability, nervousness, or restlessness
  • Insomnia
  • Headaches
  • Nausea
  • Goose bumps
  • Weakness
  • Shakiness.
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Phenylephrine Medication Information

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