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Phenylephrine Hydrochloride
Because phenylephrine comes in several forms, it can be used for a variety of different purposes. This medication comes as phenylephrine hydrochloride (in oral, nasal, injectable, cream, and eye drop forms), phenylephrine bitartrate (in effervescent tablet form), or phenylephrine tannate (in oral form). Phenylephrine is used to relieve:
- Nasal congestion due to allergies (such as hay fever) or the common cold
- Sinus congestion and pressure.
Although most people tolerate this medication well, it is not suitable for everyone. Before starting treatment, make sure to talk to your healthcare provider about any other medical conditions you may have or any other medications you are taking (including vitamins and herbal supplements). Some of the common side effects of phenylephrine include insomnia, dizziness, and nervousness.
(Click Phenylephrine for more detail on how phenylephrine works to relieve nasal and sinus congestion caused by allergies or the common cold. This article also discusses potential side effects, safety precautions, and what to tell your doctor before using this medication.)

Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD