Am I Taking Medicines That React With Phenylephrine?

Drug Interactions With Phenylephrine Explained

The following sections explain in detail the potentially negative interactions that can occur when phenylephrine is combined with any of the drugs listed above.
Iobenguane I 123
Phenylephrine may interfere with tests that use iobenguane I 123. You should not take phenylephrine for several days before a laboratory test that involves iobenguane I 123 (your healthcare provider will give you more specific instructions).
Monoamine Oxidase Inhibitors (MAOIs)
Taking phenylephrine and an MAOI together can cause life-threatening problems. Never take phenylephrine with an MAOI or even within two weeks of taking an MAOI.
Tricyclic Antidepressants
Combining phenylephrine with a tricyclic antidepressant may increase the risk for high blood pressure. If you are taking a tricyclic antidepressant, check with your healthcare provider before taking phenylephrine.

Final Thoughts

It is possible that not every phenylephrine drug interaction was discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific drug interactions that may apply to you.
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