Oxymetazoline Nasal Spray

Oxymetazoline nasal spray is used to treat nasal congestion caused by the common cold, allergies, or sinus problems. This over-the-counter medication should not be used for more than three days in a row, as prolonged use may worsen congestion. Before using this nasal spray, talk to your doctor about any other medications you are taking and any medical conditions you may have.

What Is Oxymetazoline Nasal Spray?

Oxymetazoline nasal spray (Afrin®, Nostrilla®, Sudafed OM™, and many others) is a non-prescription medication used to temporarily relieve nasal congestion due to the common cold, allergies, or sinus infections or inflammation. Because prolonged use can actually worsen congestion, this nasal spray should not be used for more than three days in a row.
(Click What Is Oxymetazoline Nasal Spray Used For? for more information, including possible off-label uses.)

Potential Side Effects of the Drug

Just like any medicine, oxymetazoline nasal spray can cause side effects. However, not everyone who takes the drug will experience problems. Most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are easily treated by you or your healthcare provider. Serious side effects are less common.
Possible side effects of oxymetazoline nasal spray include but are not limited to:
  • Temporary burning or stinging
  • Sneezing
  • Worsening of congestion with prolonged use (see Afrin Addiction).
(Click Side Effects of Oxymetazoline Nasal Spray to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
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Oxymetazoline Drug Information

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