Allergies Home > Serious Reactions to Benadryl

Serious Side Effects

Some Benadryl side effects are potentially serious and should be reported immediately to your healthcare provider. Although generally rare, some of these side effects may actually be fairly common, particularly in young children or the elderly. These include, but are not limited to:
 
  • Low blood pressure (hypotension)
  • Heart palpitations
  • A rapid heart rate (tachycardia)
  • An irregular heartbeat
  • Anemia
  • Low blood platelets
  • Confusion
  • Blurred vision or double vision
  • Loss of balance, especially if accompanied by ringing of the ears (tinnitus) or hearing loss
  • Seizures
  • Difficulty passing urine
  • Hallucinations or delirium
  • Worsening of ulcers or gastroesophageal reflux disease
  • Worsening of glaucoma
  • Signs of an allergic reaction, such as:

 

    • An unexplained rash
    • Itching
    • Hives
    • Swelling of the mouth or throat
    • Wheezing
    • Difficulty breathing.

 

Final Thoughts

You may experience some or none of the Benadryl side effects listed in this article. Unfortunately, there is no way for your healthcare provider to know beforehand if you will have side effects from a medicine that you have never tried. Therefore, make sure to let your healthcare provider know if you develop any side effects while taking the drug or if something "just does not seem right." While it may not be a side effect, your healthcare provider will be able to diagnose and treat the problem.
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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