Allergies Home > Alrex Warnings and Precautions

Before starting treatment, warnings and precautions concerning the safety of Alrex should be reviewed with your healthcare provider or pharmacist. Alrex can increase the risk of eye infections or cause perforation of the eye in certain people. It is important to talk to your healthcare provider before using Alrex if you have glaucoma or a current eye infection.

What Should I Tell My Healthcare Provider Before Taking Alrex?

You should talk with your healthcare provider prior to using Alrex® (loteprednol etabonate) if you have:
  • Glaucoma
  • An eye infection (including an inactive eye infection, which can happen with herpes)
  • Any allergies, including allergies to food, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
Make sure to tell your healthcare provider about any other medications you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Specific Precautions and Warnings With Alrex

Warnings and precautions to be aware of prior to taking Alrex include the following:
  • As a steroid, Alrex may worsen or even cause glaucoma. It is a good idea for your healthcare provider to make sure you do not have glaucoma before you start using Alrex. If you take Alrex for more than 10 days, your healthcare provider should check to make sure that Alrex is not causing glaucoma.
  • Like other steroids, Alrex can increase the risk of eye infections or reactivation of inactive infections (such as those that can occur with herpes). If you have an eye infection or a history of eye infections, check with your healthcare provider before taking Alrex. Be sure to seek medical attention if you develop an eye infection while taking Alrex.
  • Steroids can cause perforation of the eye in people who already have a thin surface of the eye (usually due to other medical conditions).
  • In order to prevent contamination of the drops, do not touch the tip of the dropper to any surface, including the surface of the eye.
  • If you wear contact lenses, you must remove them to use the drops. In order to prevent the lens from absorbing the preservative in the medication, be sure to wait 10 minutes after using the drops before reinserting the lens. Do not wear your contact lenses if your eye is still red.
  • It is unknown if Alrex passes through breast milk in significant amounts. Therefore, if you are breastfeeding or plan to start breastfeeding, discuss this with your healthcare provider prior to taking the drug (see Alrex and Breastfeeding).
  • Alrex is considered a pregnancy Category C medication. This means that it might be unsafe for use during pregnancy, although the full risks are not currently known (see Alrex and Pregnancy).
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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