More Info on Hydrocodone Polistirex/Chlorpheniramine Polistirex Indications

How Does It Work?

As mentioned, hydrocodone polistirex/chlorpheniramine polistirex contains two different medicines: hydrocodone and chlorpheniramine -- an antihistamine. Hydrocodone acts in a similar way as codeine and has several effects in the brain. One of these effects is thought to be in the "cough center" of the brain, where it helps reduce the urge to cough.
Chlorpheniramine blocks a specific type of histamine receptor in the body known as H1 receptors. Allergy symptoms, such as a runny nose, sneezing, and watery eyes, are partly caused when histamine binds to these receptors. By preventing histamine from binding to H1 receptors, chlorpheniramine helps relieve or prevent allergy symptoms.
Chlorpheniramine also blocks acetylcholine receptors, an action that produces some of the unpleasant side effects of the medication, such as dry mouth. However, blocking these specific receptors also helps to relieve a runny nose.
Hydrocodone polistirex/chlorpheniramine polistirex is an extended-release product. It has a special coating, called the Pennkinetic system, that allows the medication to be slowly released into the body. As a result, this drug stays in the body for a longer period and only needs to be taken twice a day.

Can Children Use Hydrocodone Polistirex/Chlorpheniramine Polistirex?

Hydrocodone polistirex/chlorpheniramine polistirex can be used in children as young as six years old. However, it should be used with caution in children, as they may be more sensitive to the side effects of this medicine. Children younger than six years of age should not use this drug, as cough and cold medications have not been shown to be effective or safe in young children.

Is It Safe for Older Adults?

Yes -- older adults can use this medicine. They may, however, be more sensitive to this medication and may be taking additional medications that can cause drug interactions with hydrocodone polistirex/chlorpheniramine polistirex.
Hydrocodone polistirex/chlorpheniramine polistirex is removed from the body by the kidneys. Because the kidneys begin to slow down with age, older adults may not be able to remove this medicine as quickly, causing higher levels in the body and increasing the chance of side effects.
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Hydrocodone Polistirex/Chlorpheniramine Polistirex Drug Information

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