Dymista

As a type of nasal spray, Dymista is used twice daily to help treat seasonal allergies. This prescription medicine contains both a steroid and an antihistamine. Headaches, nosebleeds, and a distorted sense of taste are just a few of the possible side effects. Dymista is approved for use in adults and children as young as 12 years old.

What Is Dymista?

Dymista™ (azelastine/fluticasone nasal spray) is a prescription medication approved to treat seasonal nasal allergies in adults and children as young as 12 years old. It contains two different medications that work in different ways to help treat nasal allergies.
 
(Click Dymista Uses for more information on this topic, including possible off-label uses.)
 

Who Makes This Medication?

Dymista is made by Meda Pharmaceuticals, Inc.
 

How Does Dymista Work?

Allergies occur as the result of the immune system's reaction to normally harmless substances that do not bother most people. This immune system reaction is known as inflammation, and involves several different types of cells and several different chemicals in the body.
 
Dymista contains two separate medications: fluticasone and azelastine. Fluticasone is a corticosteroid, or simply "steroid" for short. Steroids can have many different effects in the body, including anti-inflammatory effects. Steroids decrease inflammation by limiting the body's ability to produce an immune system reaction. They can be quite effective for treating conditions such as allergies.
 
However, long-term use of steroids can cause bothersome and sometimes serious side effects, and this limits the usefulness of many steroids. Because Dymista is a nasal spray, its effects are generally limited to the nose. This helps prevent many of the long-term side effects.
 
The other active ingredient (azelastine) is an antihistamine. Allergy symptoms are partly caused by the release of histamine from certain cells, known as mast cells. Azelastine is an antihistamine that acts in at least two different ways. It helps prevent the release of histamine from mast cells, and if any histamine is released, azelastine also prevents it from binding to histamine receptors. Because histamine is responsible for many of the symptoms of allergies, blocking it can be quite helpful.
 
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Dymista Drug Information

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