Dymista Uses

How Does It Work?

Allergies occur as the result of the immune system's reaction to normally harmless substances that do not bother most people. This reaction is known as inflammation, and it involves several different types of cells and several different chemicals in the body.
Dymista contains two separate medications: fluticasone and azelastine. Fluticasone is a corticosteroid, or simply "steroid" for short. Steroids can have many different effects in the body, including anti-inflammatory effects. Steroids decrease inflammation by limiting the body's ability to produce an immune system reaction. They can be quite effective for treating conditions such as allergies.
However, long-term use of steroids can cause bothersome and sometimes serious side effects, and this limits the usefulness of many steroids. Because Dymista is a nasal spray, its effects are generally limited to the nose. This helps prevent many of the long-term steroidal side effects.
The other active ingredient (azelastine) is an antihistamine. Allergy symptoms are partly caused by the release of histamine from certain cells, known as mast cells. Azelastine is an antihistamine that acts in at least two different ways. It helps prevent the release of histamine from mast cells, and if any histamine is released, azelastine also prevents it from binding to histamine receptors. Because histamine is responsible for many of the symptoms of allergies, blocking it can be quite helpful.

Is It Safe for Children to Use Dymista?

Dymista is approved to treat nasal allergies in children as young as 12 years old; it has not yet been adequately studied in younger children. Talk to your healthcare provider about the benefits and risks of using this medication in children.

Off-Label Dymista Uses

On occasion, a healthcare provider may recommend this product for something other than treating nasal allergies. This is called an "off-label" use. Currently, off-label uses of Dymista include treatment of the following conditions:
  • Perennial (year-round) allergies
  • Nasal symptoms not caused by allergies (known as nonallergic rhinitis).
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Dymista Drug Information

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