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Side Effects of Claritin-D
In clinical studies of Claritin-D, insomnia, dry mouth, and drowsiness were the most commonly reported side effects. Other, less common side effects (occurring in 2 to 3 percent of people) included cough, nausea, and loss of appetite. There are also several rare but potentially serious Claritin-D side effects that may require medical attention, such as chest pain, high blood pressure, and seizures.
As with any medicine, side effects are possible with Claritin-D® (loratadine and pseudoephedrine sulfate). However, not everyone who takes the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or can easily be treated by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Claritin-D. Your healthcare provider can discuss a more complete list of Claritin-D side effects with you.)
Claritin-D has been studied thoroughly in clinical trials, in which the side effects of a group of people taking the drug are documented and compared to another group not taking the medicine. As a result, it is possible to see what side effects occur, how often they appear, and how they compare to the group not taking the medicine.
In these studies, the most common side effects of Claritin-D in adults included:
- Insomnia -- in up to 16 percent of people (see Claritin-D and Insomnia)
- Dry mouth -- up to 14 percent
- Drowsiness -- up to 7 percent
- Nervousness -- up to 5 percent
- Dizziness -- up to 4 percent
- Fatigue -- up to 4 percent.
Other common side effects (occurring in 2 to 3 percent of people) included:
- Indigestion or heartburn
- Nausea
- Loss of appetite
- Thirst
- Cough
- Painful menstrual periods.
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD



