Claritin-D Interactions

Certain drugs, such as monoamine oxidase inhibitors, blood pressure medications, or ketoconazole, may interact with Claritin-D. Interactions with these medicines could increase the level of Claritin-D in your blood and increase your risk of developing side effects. Since drug interactions with Claritin-D are usually due to the pseudoephedrine component of the medication, regular Claritin (which does not contain pseudoephedrine) may be a better choice.

 

An Overview of Claritin-D Interactions

Claritin-D® (loratadine and pseudoephedrine sulfate) can potentially interact with a few other medications. Some of the medicines that may lead to Claritin-D drug interactions include:
 
  • Blood pressure medications
  • Cimetidine (Tagamet®)
  • Digoxin (Digitek®, Lanoxin®)
  • Erythromycin (Ery-Tab®)
  • Ketoconazole (Nizoral®)
  • Monoamine oxidase inhibitors (MAOIs), such as:
 
 

Claritin-D Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Claritin-D is combined with any of the drugs listed above.
 
Blood Pressure Medications
Claritin-D may make blood pressure medications less effective, possibly causing high blood pressure (hypertension). This is due to the pseudoephedrine component of Claritin-D. If you take high blood pressure medications, check with your healthcare provider before taking Claritin-D or try regular Claritin instead, which does not contain pseudoephedrine and does not increase blood pressure.
(Claritin-D Interactions Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;