Claritin-D Interactions (Cont.)

 
Cimetidine
Erythromycin may increase the level of Claritin-D in the blood, although studies suggest that this interaction is unlikely to cause any problems. However, you may want to consult your healthcare provider, especially if you notice any increase in side effects of Claritin-D.
 
Digoxin
Taking Claritin-D with digoxin can increase the risk of an irregular heart rhythm (arrhythmia). Check with your healthcare provider before taking these medications together. Because this interaction is due to the pseudoephedrine component of Claritin-D, regular Claritin, which does not contain pseudoephedrine, will not cause similar problems.
 
Erythromycin
Taking Claritin-D with erythromycin may change the way your body handles Claritin-D, increasing the level of the drug in your blood. However, this interaction seems unlikely to cause problems for most people.
 
Ketoconazole
Combining ketoconazole with Claritin-D may increase the level of Claritin-D in your blood, although studies have not shown this to be a problem for most people.
 
Monoamine Oxidase Inhibitors
Combining Claritin-D with an MAOI can cause serious problems. Do not take Claritin-D while taking an MAOI (or even within two weeks of stopping an MAOI). This interaction is due to the pseudoephedrine component of Claritin-D; regular Claritin does not contain pseudoephedrine and does not cause similar problems.
 

Final Thoughts on Claritin-D Interactions

It is possible that not all Claritin-D interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific drug interactions that may apply to you.
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;