Bepreve™ (
bepotastine besilate) is a prescription medication approved for treating eye itching caused by
allergies. It comes in the form of an eye drop.
Bepreve is manufactured by Bausch & Lomb, Inc., for ISTA Pharmaceuticals, Inc.
Bepreve is part of a class of drugs known as H1 receptor antagonists, commonly known as antihistamines. It works by blocking a specific type of histamine receptor in the body known as H1 receptors. Since allergic reactions are partly caused by the release of histamine from certain cells in the body, Bepreve can help relieve or prevent
allergy symptoms.
In addition to blocking histamine receptors, Bepreve seems to decrease the release of histamine from cells in the body.
In clinical studies, this medication was shown to relieve itching of the eyes due to allergies.
The studies showed that Bepreve was more effective than a placebo eye drop (the same formulation, minus the active ingredient) for relieving eye itching.