Dosing for Benadryl® (diphenhydramine hydrochloride) varies depending on the particular product you are taking. For the treatment of allergy or cold symptoms in adults and older children, the recommended dosage is 25 to 50 mg every four to six hours. The recommended dosage for children 6 to 12 years old is 12.5 to 25 mg. For Benadryl cream, spray, stick, or gel, a small amount of the product should be applied to the skin no more than three or four times daily.
(Click Benadryl Dosage to find out how Benadryl dosing works for other conditions and for tips on using this medication. You can also click on the various links in the box to the right to access specific topics on Benadryl.)
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