Specific Drugs That React With Actifed

Actifed Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Actifed is combined with any of the drugs listed above.
 
Alcohol
You should avoid alcohol while taking Actifed, as undesirable side effects (such as excessive drowsiness, dizziness, or confusion) may result.
 
Acetylcholinesterase Inhibitor Medications
Actifed can make acetylcholinesterase inhibitor medications less effective. Check with your healthcare provider before combining these medications.
 
Anticholinergic Drugs
Combining an anticholinergic medication with Actifed can increase your risk of side effects, such as dry mouth, constipation, dry eyes, or difficulty passing urine. Check with your healthcare provider before taking these medications together.
 
Iobenguane I 123
Actifed may interfere with tests that use iobenguane I 123. You should not take Actifed for several days before a laboratory test that involves iobenguane I 123 (your healthcare provider will give you more specific instructions).
 
Monoamine Oxidase Inhibitors (MAOIs)
Taking Actifed and an MAOI together can cause life-threatening problems. Never take Actifed with an MAOI or even within two weeks of taking an MAOI.
 
Other Medications That Cause Drowsiness
Check with your healthcare provider before combining Actifed with any other medication that also causes drowsiness, as undesirable side effects (such as excessive drowsiness, dizziness, or confusion) may result.
 
Phenothiazines
Actifed may increase the risk of a dangerous irregular heart rhythm (arrhythmia) due to a phenothiazine medication. In addition, combining Actifed with a phenothiazine increases the risk of excessive drowsiness.
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